Chargaff, Erwin Essay, Research Paper
Erwin Chargaff
Erwin Chargaff, born 1905 in Czernowiz, Austria, was a pioneer in biochemistry
contributing to the understanding of DNA. He, in 1928, earned his doctoral degree in
chemistry at the University of Vienna’s Spath’s Institute in 1928. Erwin began his career
in biochemistry at Yale University, working under Rudolph J. Anderson from 1928 to
1930. His early work included stories of the complex lipids, the fats or fatty acids that
occur in microorganisms. Helping discover the unusual fatty acids and waxes in
acid-fast mycobacteria led him to study the metabolism and biological role of lipids in
the body. Chargaff was also a pioneer in the use of radioactive isotopes of phosphorus as
a tool to study in the synthesis and breakdown of phosphorus-containing lipid molecules
in living cells. He published a paper on the synthesis of a radioactive organic compound
called alpha-glycerophosphoric acid. He began to study nucleic acids in 1944, while at
Colombia. Until this time scientists believed that amino acids carried genetic
information. DNA was also believed to contain the tetranucleotides made up of cytosine,
thymine, adenine and guanine, that served as an attachment site for the amino acids that
made up genes. It was already known that a cell’s nucleus is comprised in part by DNA,
Chargaff was able to determine how much of which bases were present by measuring the
amount of light each quantity of base absorbed. He showed that adenine and thymine
occur in DNA in equal proportions in all organisms and that cytosine and guanine are
also found in equal quantities. Chargaff’s major conclusion is that DNA carries genetic
information, and the number of different combinations in which the four nucleic acids
appear in DNA provides enough complexity to form the basis of heredity. Finally, he
concluded that the identity of combinations differs from species to species and that DNA
strands differ from species.
Overall, his findings were important contributions in biochemistry, including the
addition of a key piece in the puzzle of the structure of DNA. This all led to major
developments in the field of medical genetics, and, ultimately helped pave the way for
gene therapy and the birth of the biotechnology industry.
Другие работы по теме:
Майер, Христиан
Христиан Майер (нем. Christian Mayer (1719 −1783)) — немецкий учёный-иезуит, астроном, физик, геодезист, картограф и меторолог. Биография Родился в Модрице (близ Брно, Моравия), в 1745 вступил в орден иезуитов. С 1752 — профессор математики и физики, с 1762 — профессор астрономии Гейдельбергского университета.
Киш, Эгон Эрвин
Эгон Эрвин Киш (нем. Egon Erwin Kisch, 29 апреля 1885, Прага, Австро-Венгрия — 31 марта 1948, Прага, Чехословакия) — чешско-немецкий писатель и журналист, участник гражданской войны в Испании.
Romeel The Desert Fox Essay Research Paper
Rommel: the Desert Fox Erwin Rommel Jr. was born on November 15, 1891. As a child, he was even tempered and was unremarkable academically and athletically. During adolescence, he became very adept at mathematics (His father and grandfather were both distinguished mathematicians.) Jr. always preferred practical books to works of imagination.
Romeo An Juliet Essay Research Paper hi
Romeo An Juliet Essay, Research Paper hi i need an essay about a character in romeo and juliet that demonsrtated maturity. in a well developed multi pagraph essay and say why you think the character’s maturity was greater than the other characters in the play.
Chaos Vs Order Essay Research Paper The
Chaos Vs. Order Essay, Research Paper The short story by James Thurber, “The Catbird Seat”, describes a man, Mr. Erwin Martin, who is very precise and logical in everything he does including his job and
Oh Really Essay Research Paper Oh Reallyyou
Oh Really? Essay, Research Paper Oh Really, you think i am a lark, the dogs they run and bark, but when i say to them, shut up shut up shut up, you say to be nice to them,
The Catbird Seat Essay Research Paper The
The Catbird Seat Essay, Research Paper The Catbird Seat In ?The Catbird Seat? Erwin Martin, a diligent employee of F & S for twenty-two years, is driven insane by new co-worker, Ulgine Barrows. Mr. Martin is a very conservative man who has never taken a drink or smoked in his life. Mr. Martin despises her ?quacking? voice and ?braying? laugh.
From The Inside Out Essay Research Paper
From the Inside Out James Thurber?s short story ?The Catbird Seat,? begins in medias res. Thurber introduces us to Mr. Erwin Martin, a structured individual entertaining thoughts of casual lunacy amongst his otherwise pedantic existence. The suspense in the short story is triggered even before the plot unfolds for it is clear that Mr.
Driving Offences Essay Research Paper My research
Driving Offences Essay, Research Paper My research paper is on "Drinking and Driving Offences". In my paper I will tell you the various kinds of drinking and driving offences, the penalties, and the defenses you can make if you are caught drinking and driving.
Shane Essay Research Paper Sometimes I need
Shane Essay, Research Paper Sometimes, I need you more than I need air And sometimes I miss you more than I will forever, never forget the times that we have shaared. The are priceless
Poem Belong Essay Research Paper Where I
Poem: Belong Essay, Research Paper Where I belong I am weak, I am strong I will fit where I belong don’t know where it is for now but it will come, if I allow tomorrow, I start a brand new day
Him Essay Research Paper I think about
Him Essay, Research Paper I think about him day and night The though won’t go away And, oh, how I would hold him tight every second of the day He is perfect, that is true, not an average me or you
Rommel Erwin Essay Research Paper Rommel Erwin
Rommel, Erwin Essay, Research Paper Rommel, Erwin (Johannes Eugen) 1891 German field marshal, born in Heidenheim, Germany. He studied at T bingen, fought in World War 1, taught at Dresden Military Academy, and became an early Nazi sympathizer. He commanded Hitler’s headquarters guard during the early occupations, and led a Panzer division during the 1940 invasion of France.
Poem She Sat Essay Research Paper She
Poem: She Sat Essay, Research Paper She sat… helpless in her room praying to whatever god there may be to let her call to him. could god ignore such a painful cry?
Ode To Boys Essay Research Paper We
Ode To Boys Essay, Research Paper We like them But do they like us The ones we do never fuss They don’t stop in And we wonder why We stress, we bitch We sometimes cry
Dna Four Bases Essay Research Paper In
Dna Four Bases Essay, Research Paper In the early 1950’s, the structure of DNA had become a crucial puzzle, following the discovery that DNA and not protein was the “transforming” principle. The puzzle was more intriguing because of the challenge of figuring out how a polymer composed of only 4 different “letters” could encode for a polymer such as proteins that are composed of 20 different letters.
Structure Of Dna Essay Research Paper The
Structure Of Dna Essay, Research Paper The ?Thread of Life?, is deoxyribonucleic acid, also known as DNA. This molecule which is the bases of life, is spiral shaped and found in the nucleus of cells. DNA has the genetic code for bodies, controls development of embryo?s, and is able to repair damage caused to itself.
Life Is Like Essay Research Paper Life
Life Is Like Essay, Research Paper Life is like a car. When it?s new, it usually works all right. As time drives by, it breaks down and needs repairs. Life is like a leaf. In its youth, it
The American Dream 2 Essay Research Paper
Thomas Jefferson described the American Dream as life, liberty, and the pursuit of happiness. Every person has a dream and in the three short stories, The Catbird Seat by James Thurber, Winter Dream by F. Scott Fitzgerald and A Rose for Emily by William Faulkner, the theme is one common American Dream: happiness.
Dare Essay Essay Research Paper What DARE
Dare Essay Essay, Research Paper What D.A.R.E Means To Me Dare has prepared me to say no to drugs in eight different ways. If anyone asks me to do drugs I will know what to do, such as- just ignoring the person or just
Black Holes Essay Research Paper Erwin Floresca593502170
Black Holes Essay, Research Paper Erwin Floresca 593-50-2170 AST 2006-001 Dr. Carol A. Williams Black Holes As the nighttime sky falls upon us and we gaze at the beautiful stars, imagination takes one away from the limits of our solar system to the depths of a high-mass black hole. The universe that we live in contains unique and exciting matter that interests us to learn about all the variances that may only be viewed through a telescope.
Desert Fox Essay Research Paper Desert Fox
Desert Fox Essay, Research Paper Desert Fox Erwin Rommel was born in 1891. As field marshal he was known best for his capture of 9,000 allied forces during World War I. On the Germans invasion of France in 1940, Rommel commanded the well-known Ghost Division or otherwise known as the German 7th Panzer Division.
The Search For The Double Helix Essay
, Research Paper This is an excellent story autobiography, of a brilliant scientist, James Dewey Watson, who reveals the structure of DNA. But this book is not wholly about science. Far from it. It’s about a race, or game, for the one thing that separates scientists from great scientists, the Nobel Prize.